Hailey is a licensed practical nurse at an assisted living facility for the elderly. She has lived with depression (MDD) for 15 years.
Hailey is 31 years old and married with a busy day-to-day schedule. In her spare time she enjoys crocheting and “hanging out” with her husband.
Hailey started experiencing symptoms of depression early in life
When she was younger, Hailey had a strong sense that something wasn’t right, but she didn’t know what the word was for it. She found herself crying a lot. As she got older, her symptoms got worse. She felt sad, and just didn’t care about things. She was tired all the time, felt worthless, and had difficulty concentrating and making decisions. At the time, she filled out a questionnaire with her family doctor, and he explained that she had major depressive disorder.
Two years ago, Hailey began to feel like things were unravelling
After her diagnosis, Hailey's doctor suggested a treatment plan that helped her feel better at first. However, over time, she felt her depressive symptoms return. In 2014, she had what she describes as her worst depressive episode. She began to cry two to three hours each day, felt fatigued and lost motivation to get out of bed. “I just felt worthless, and didn't care about things like I used to,” she remembers. Hailey felt trouble concentrating was becoming a more common occurrence. She found this frustrating because as a nurse, she felt like she should know how to deal with her symptoms. Hailey finally realized she could no longer manage on her own and she reached out to her doctor.
People with depression (MDD) suffer with 5 or more of the following symptoms including either depressed mood or decreased interest or pleasure for 2 or more weeks:
- Depressed mood
- Loss of interest or pleasure
- Diminished ability to think or concentrate, or indecisiveness
- Insomnia or hypersomnia
- Psychomotor agitation or retardation
- Fatigue or loss of energy
- Feelings of worthlessness or excessive guilt
- A significant change in weight or appetite
- Suicidal ideation
Hailey’s doctor discussed treatment options
Hailey discussed her depression symptoms with her doctor, and during the appointment, her doctor suggested TRINTELLIX – a prescription medicine used to treat major depressive disorder in adults.
TRINTELLIX (vortioxetine) is a prescription medicine used to treat Major Depressive Disorder (MDD) in adults.
Hailey knows the importance of sharing with your doctor
After starting TRINTELLIX, Hailey noticed that her depression symptoms were improving. "My depression was less of a struggle," she reports. "I felt like my treatment was working for me." Her experiences have taught her how important the relationship with her doctor is. "When talking to a doctor… start by sharing about your symptoms," she explains. "I’ve learned that even the littlest details can help. Trust me, I’m a nurse."
TRINTELLIX helped reduce the multiple symptoms of depression (MDD) based on an overall score on a standardized depression rating scale in multiple 6-8 week studies and one maintenance study vs. sugar pill.
In short-term studies, the therapeutic effect of TRINTELLIX was generally seen starting at week 2, with full effect generally not seen until week 4, or later.
Individual results may vary.
Patients featured are on TRINTELLIX at time of interview.
Patients featured are on TRINTELLIX at time of interview.
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Suicidal Thoughts and Actions and Antidepressant Drugs
Antidepressants may increase suicidal thoughts or actions in some children, teens or young adults within the first few months of treatment or when the dose is changed. Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions. People who have (or have a family history of) bipolar illness, or suicidal thoughts or actions may have a particularly high risk. Pay close attention to any changes, especially sudden changes in mood, behavior, thoughts or feelings. Call your healthcare provider right away if symptoms such as anxiety, irritability, impulsivity, trouble sleeping, aggressive behavior or suicidal thoughts are new, worse or worry you. TRINTELLIX has not been evaluated for use in patients under 18.
Do not take TRINTELLIX if you:
- Are allergic to vortioxetine or any of the ingredients in TRINTELLIX
- Take a Monoamine Oxidase Inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid; do not take an MAOI within 21 days of stopping TRINTELLIX; do not start TRINTELLIX if you stopped taking an MAOI in the last 14 days
TRINTELLIX may cause serious side effects including:
Serotonin Syndrome: A potentially life-threatening problem that can happen when medicines such as TRINTELLIX are taken with certain other medicines. Symptoms may include agitation, hallucinations, coma or other changes in mental status; problems controlling movements or muscle twitching, stiffness or tightness; fast heartbeat, high or low blood pressure; sweating or fever; nausea, vomiting or diarrhea.
Abnormal bleeding or bruising: TRINTELLIX and other serotonergic antidepressant medicines may increase your risk of bleeding or bruising, especially if you take the blood thinner warfarin (Coumadin®, Jantoven®), a non-steroidal anti-inflammatory drug (NSAID), or aspirin.
Manic episode: Symptoms may include greatly increased energy; severe trouble sleeping; racing thoughts; reckless behavior; unusually grand ideas; excessive happiness or irritability; talking more or faster than usual.
Visual problems: May include eye pain, changes in vision, swelling or redness in or around the eye. Only some people are at risk for these problems. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are.
Low salt (sodium) levels in the blood: Symptoms may include headache; difficulty concentrating, memory changes or confusion; weakness and unsteadiness on your feet; and in severe or sudden cases hallucinations, fainting, seizures or coma. If not treated, severe low sodium levels can cause death.
Before starting TRINTELLIX, tell your healthcare provider if you have or had liver problems, seizures or convulsions, bipolar disorder (manic depression) or mania, low salt (sodium) levels in your blood, bleeding problems, drink alcohol, have any other medical conditions or if you are pregnant, nursing, plan to become pregnant, or plan to nurse.
TRINTELLIX and some medicines may interact with each other, may not work as well, or may cause serious side effects when taken together. Tell your healthcare provider if you plan on or are taking any other prescription and non-prescription medicines, vitamins and herbal supplements including medicines for migraine headaches, such as triptans; medicines used to treat mood, anxiety, psychotic or thought disorders such as tricyclics, lithium, SSRIs, SNRIs, bupropion, buspirone or antipsychotics; MAOIs including linezolid (a specific antibiotic); over-the-counter supplements such as tryptophan or St. John's wort; and the following medicines: aspirin, NSAIDs, warfarin (Coumadin®, Jantoven®), diuretics, rifampin, carbamazepine, phenytoin, quinidine, tramadol or fentanyl.
Common side effects of TRINTELLIX include: nausea, constipation or vomiting. These are not all the possible side effects of TRINTELLIX.
Do not start or stop taking TRINTELLIX without talking to your healthcare provider first. Suddenly stopping TRINTELLIX when you take higher doses may cause you to have side effects including headache, stiff muscles, mood swings, sudden outbursts of anger, dizziness or feeling lightheaded, or runny nose.
Talk to your healthcare provider.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or
Indication for TRINTELLIX
TRINTELLIX is a prescription medicine used to treat Major Depressive Disorder (MDD) in adults.