When you think of life with Major Depressive Disorder, or MDD, what do you see? People may think they know exactly what MDD looks like. But the truth is that MDD looks different for everyone, because everyone experiences it differently. To get a more authentic picture of MDD, we have to look at not just the disorder, but also some people living with it. Because when a patient works with their doctor to find the treatment plan that’s right for them, it may have a noticeable impact on their MDD. That’s what I want other patients to know. Who am I? My name is Jesus. My name is Ruth. Hi, I am Tatiana. Our doctors told us about TRINTELLIX, a prescription medicine for adults with a type of depression called Major Depressive Disorder, or MDD. Now, we’ve become the first TRINTELLERS, a collection of actual TRINTELLIX patients who are telling personal stories of our lives with MDD. Each of us will be recording one second of our lives every day, as well as telling you about our recent experiences with MDD, working with our doctors, and our journey with TRINTELLIX.

Antidepressants, like TRINTELLIX, may increase suicidal thoughts and behaviors in children, teens, and young adults. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in mood, behavior, or thoughts of suicide while taking it. Do not take it if you take MAOIs, are allergic to vortioxetine or any other ingredients in TRINTELLIX. Tell your doctor about all medicines you take, including migraine, psychiatric, and depression medicines, to avoid a potentially life-threatening condition. Increased risk of bleeding and bruising may occur, especially if taken with NSAID pain relievers, aspirin, or blood thinners. Manic episodes can occur. Call your doctor if you have any unusual changes in mood, behavior, or thoughts. Visual problems may occur in some people. TRINTELLIX may cause low sodium levels. Common side effects include nausea, constipation, and vomiting.

Although we know there isn’t a cure for MDD and that we’ll continue to face challenges, we want to start the conversation and raise awareness for others who may be living with MDD. Together, we hope to encourage other MDD patients to work with their doctor to find the treatment plan that works for them. Thank you and see y’all soon.

Real Stories from people taking TRINTELLIX. Meet the TRINTELLERS.

TRINTELLIX + Storytellers = TRINTELLERS.

TRINTELLERS are real MDD patients treated with TRINTELLIX who are here to share their stories with others.

 

Major Depressive Disorder (MDD) has many faces. Here, we get an inside look at the lives of a few TRINTELLIX (vortioxetine) patients who are sharing what life with MDD is like for them.

Patient Stories

MEET JESUS

My name is Jesus, I have MDD which has multiple symptoms that can hold me back. I’m a dog dad, a friend, and sometimes I’m an amateur karaoke singer. My life motto is to try and find the good things even in bad situations.

My doctor prescribed TRINTELLIX, a prescription medicine for adults with a type of depression called Major Depressive Disorder, or MDD. Since then, I’ve found improvement in my overall MDD symptoms. 

Antidepressants, like TRINTELLIX, may increase suicidal thoughts and behaviors in children, teens, and young adults. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in mood, behavior, or thoughts of suicide while taking it. Do not take it if you take MAOIs, are allergic to vortioxetine, or any other ingredients in TRINTELLIX. Tell your doctor about all medicines you take, including migraine, psychiatric, and depression medicines, to avoid a potentially life-threatening condition. Increased risk of bleeding and bruising may occur, especially if taken with NSAID pain relievers, aspirin, or blood thinners. Manic episodes can occur. Call your doctor if you have any unusual changes in mood, behavior or thoughts. Visual problems may occur in some people. TRINTELLIX may cause low sodium levels. Common side effects include nausea, constipation, and vomiting.

I’m sharing my story because I want to help connect with other people who have depression and show them that they’re not alone. So talk to your doctor to find a treatment plan that’s right for you.

My life motto is to try and find the good things even in bad situations.

Learn more about Jesus' story

MEET RUTH

My name is Ruth. I have MDD which has multiple symptoms that can hold me back. I’m an avid reader, I love to travel, and work on puzzles. My motto is to embrace gratitude and try my best every day. My doctor prescribed TRINTELLIX, a prescription medicine for adults with a type of depression called Major Depressive Disorder. Since then, I’ve found improvement in my overall MDD symptoms.

Antidepressants, like TRINTELLIX, may increase suicidal thoughts and behaviors in children, teens, and young adults. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in mood, behavior, or thoughts of suicide while taking it. Do not take it if you take MAOIs, are allergic to vortioxetine, or any other ingredients in TRINTELLIX. Tell your doctor about all medicines you take, including migraine, psychiatric, and depression medicines, to avoid a potentially life-threatening condition. Increased risk of bleeding and bruising may occur, especially if taken with NSAID pain relievers, aspirin, or blood thinners. Manic episodes can occur. Call your doctor if you have any unusual changes in mood, behavior, or thoughts. Visual problems may occur in some people. Trintellix may cause low sodium levels. Common side effects include nausea, constipation, and vomiting.

I’m sharing my story because I want to encourage others to not give up, and to seek whatever help they may need. So, talk to your doctor, and find a treatment plan that’s right for you.

My motto is to embrace gratitude and try my best every day.

Learn more about Ruth's story

MEET TATIANA

My name is Tatiana, I have MDD which has multiple symptoms that can hold me back. When I’m not traveling, I like to play video games, watch tv, and hang out with my cat. My life motto is “It’s okay to not be okay”. So my doctor told me about TRINTELLIX, a prescription medicine for adults with a type of depression called Major Depressive Disorder, or MDD. Since then, I’ve found improvement in my overall MDD symptoms.

Antidepressants, like TRINTELLIX, may increase suicidal thoughts and behaviors in children, teens, and young adults. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in mood, behavior, or thoughts of suicide while taking it. Do not take it if you take MAOIs, are allergic to vortioxetine, or any other ingredients in TRINTELLIX. Tell your doctor about all medicines you take, including migraine, psychiatric, and depression medicines, to avoid a potentially life-threatening condition. Increased risk of bleeding and bruising may occur, especially if taken with NSAID pain relievers, aspirin, or blood thinners. Manic episodes can occur. Call your doctor if you have any unusual changes in mood, behavior, or thoughts. Visual problems may occur in some people. Trintellix may cause low sodium levels. Common side effects include nausea, constipation, and vomiting.

I’m sharing my story because I want others to know what having MDD may look like and that getting help from your doctor may have a noticeable impact on your MDD. So talk to your doctor to find a treatment plan that’s right for you.

My motto is "it's okay not to be okay".

Learn more about Tatiana's story

Jesus' Story

After struggling with his MDD symptoms for many years, Jesus finally decided to talk to his doctor, who prescribed him TRINTELLIX. Learn more about his treatment journey and what life with MDD looks like for him today.

Before I was diagnosed with Major Depressive Disorder, I was dealing with my symptoms on my own, not knowing what was really going on. Going through that was really hard for me, and the people around me noticed how I was struggling with my MDD. Living with MDD is challenging and you can’t even hope to start dealing with it if you don’t talk to your doctor and find the treatment plan that is right for you. I’ve dealt with multiple MDD symptoms that have affected me emotionally. Sometimes I feel sad, I lost interest in things I enjoyed, and I’ve noticed a considerable change of my weight. Between these and the other symptoms I felt, it made me realize I couldn’t continue like this forever, and I needed to do something about it. That’s what really convinced me to talk to a doctor. And when I finally did, my doctor told me about TRINTELLIX, a prescription medicine for adults with a type of depression called Major Depressive Disorder. Looking back, I definitely should have talked to a doctor earlier. There’s good days and there’s bad days, it’s never perfect. But TRINTELLIX has helped by giving me improvement in my overall MDD symptoms.

Antidepressants, like TRINTELLIX, may increase suicidal thoughts and behaviors in children, teens, and young adults. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in mood, behavior, or thoughts of suicide while taking it. Do not take it if you take MAOIs, are allergic to vortioxetine, or any other ingredients in TRINTELLIX. Tell your doctor about all medicines you take, including migraine, psychiatric, and depression medicines, to avoid a potentially life-threatening condition. Increased risk of bleeding and bruising may occur, especially if taken with NSAID pain relievers, aspirin, or blood thinners. Manic episodes can occur. Call your doctor if you have any unusual changes in mood, behavior, or thoughts. Visual problems may occur in some people. TRINTELLIX may cause low sodium levels. Common side effects include nausea, constipation, and vomiting.

Feeling this overall MDD symptom relief; it’s been a real change. I’m looking forward to continuing to work with my doctor on my MDD treatment plan, and seeing what comes next. 

Ruth's Story

Ruth's journey to treatment was helped by being open with her doctor and the support of her family. It took years for her to find the right treatment plan, including TRINTELLIX. Hear her story in her own words and see what her life with MDD looks like today.

When I think about Major Depressive Disorder, or MDD, I think about all the people who are probably like me. People who are struggling, and just want to find a way to feel better. I was working with my doctor to try to find the right treatment plan for me, but it didn’t happen in a day. Eventually we found the right one for me, but it took a little bit to get there, and during that time I was dealing with MDD, which has multiple symptoms. I felt sad a lot of the time, and I felt a lot of fatigue. I suddenly had no interest in the things I used to care about. I think having support is important. My sister was always there for me. She actually encouraged me to keep working with my doctor, and not to give up. That was when my doctor started talking about TRINTELLIX, a prescription medicine that treats a type of depression called Major Depressive Disorder in adults. After some discussions, my doctor and I realized this is a medication that might be able to help as part of my treatment plan.

Antidepressants, like TRINTELLIX, may increase suicidal thoughts and behaviors in children, teens, and young adults. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in mood, behavior, or thoughts of suicide while taking it. Do not take it if you take MAOIs, are allergic to vortioxetine, or any other ingredients in TRINTELLIX. Tell your doctor about all medicines you take, including migraine, psychiatric, and depression medicines, to avoid a potentially life-threatening condition. Increased risk of bleeding and bruising may occur especially if taken with NSAID pain relievers, aspirin, or blood thinners. Visual problems may occur in some people. TRINTELLIX may cause low sodium levels. Common side effects include nausea, constipation, and vomiting. Manic episodes can occur. Call your doctor if you have any unusual changes in mood, behavior, or thoughts.

Sure, I have bad days and I face challenges, but having this treatment plan in place and working with my doctor, it’s helped manage my MDD. I know that if I continue being open with the people in my life who are there to support me, and stick to my prescribed plan, I’ll be able to continue on this MDD treatment journey. Even though I know there will be challenges, I’m looking forward to seeing what’s next. 

Tatiana's Story

Tatiana's MDD journey was not easy, but she and her doctor never gave up. Check out her story and learn how they came to find a treatment plan that works for her.

My road to finding the right treatment plan for my Major Depressive Disorder, or MDD... wasn’t easy. It wasn’t quick. It took a long time. If I’m being honest, I had forgotten what it felt like to not be sad all the time. Through it all, I was trying to deal with MDD, which has multiple symptoms, by myself. But it was too much to handle alone. It’s important to come to terms with being open about how you’re feeling and accepting that someone may be able to help you, and it’s really important to talk to a doctor. I often feel sad. I’ve lost interest in things I used to care about and I have trouble concentrating. I’ve realized that I can’t handle these and other symptoms of MDD on my own. That’s when I began working with my doctor who prescribed me TRINTELLIX, a prescription medicine for adults with a type of depression called Major Depressive Disorder. So far, I’ve been feeling improvement in my overall MDD symptoms.

Antidepressants, like TRINTELLIX, may increase suicidal thoughts and behaviors in children, teens, and young adults. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in mood, behavior, or thoughts of suicide while taking it. Do not take it if you take MAOIs, are allergic to vortioxetine, or any other ingredients in TRINTELLIX. Tell your doctor about all medicines you take, including migraine, psychiatric, and depression medicines, to avoid a potentially life-threatening condition. Increased risk of bleeding and bruising may occur, especially if taken with NSAID pain relievers, aspirin, or blood thinners. Manic episodes can occur. Call your doctor if you have any unusual changes in mood, behavior, or thoughts. Visual problems may occur in some people. TRINTELLIX may cause low sodium levels. Common side effects include nausea, constipation, and vomiting.

You’ve gotta be open about how you’re feeling, gotta speak up to your doctor, continue working together, and looking for the right treatment plan for you. It’s gonna be a long road, and I know there will be obstacles, but there may be a light at the end of the tunnel. And if you decide to talk to a doctor, you’ll be proud that you decided to try and do something about your MDD. I’m gonna continue on this journey, because it’s worth it to me.

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Ready to tell it like it is about your journey with Major Depressive Disorder?

If you have been diagnosed with Major Depressive Disorder (MDD) and are taking TRINTELLIX, consider sharing your story with us. Sharing your personal journey may encourage others struggling with MDD to talk to their healthcare professionals about their treatment plan. Your MDD story will provide a first-hand account of the realities of coping with the symptoms, and your personal treatment experience with TRINTELLIX.

In order to reach other people with MDD, you may be invited to share your story in video, print, or web materials, or to participate in market research. Participation is voluntary and you can stop participating at any time.

IMPORTANT SAFETY INFORMATION About TRINTELLIX

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Suicidal Thoughts & Actions

TRINTELLIX and other antidepressants may increase suicidal thoughts and actions in some people 24 years of age and younger, especially within the first few months of treatment or when the dose is changed. TRINTELLIX is not for use in children under 18. Depression or other mental illnesses are the most important causes of suicidal thoughts or actions. Pay close attention to any changes, especially new or sudden changes in mood, behavior, thoughts, or feelings. Call your doctor or get emergency help right away if you have symptoms such as suicidal thoughts or actions, impulsivity, aggressive or violent actions, depression, anxiety or panic attacks, agitation, restlessness, anger, irritability, trouble sleeping, an increase in activity or talking, or other unusual changes in behavior or mood; especially if they are new, worse, or worry you.

Who should not take TRINTELLIX?

Do not start or take TRINTELLIX if you:

  • are allergic to vortioxetine or any of the ingredients in TRINTELLIX
  • take a Monoamine Oxidase Inhibitor (MAOI)
  • have stopped taking an MAOI in the last 14 days
  • are being treated with the antibiotic linezolid or intravenous methylene blue

Do not start taking an MAOI for at least 21 days after you stop treatment with TRINTELLIX.

What should I tell my doctor before taking TRINTELLIX?

Before taking TRINTELLIX, tell your doctor:

  • about all your medical and other health conditions
  • if you are pregnant or plan to become pregnant, since TRINTELLIX may harm your unborn baby. Taking TRINTELLIX during your third trimester may cause your baby to have withdrawal symptoms after birth or to be at increased risk for a serious lung problem at birth. Tell your doctor right away if you become or think you are pregnant while taking TRINTELLIX.
  • if you are breastfeeding or plan to breastfeed, since it is not known if TRINTELLIX passes into your breast milk

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, since TRINTELLIX and some medicines may cause serious side effects (or may not work as well) when taken together. Especially tell your doctor if you take: medicines for migraine headache called triptans; tricyclic antidepressants; fentanyl; lithium; tramadol; tryptophan; buspirone; St. John’s Wort; medicines that can affect blood clotting such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin; and diuretics.

What are the possible side effects of TRINTELLIX?

TRINTELLIX may cause serious side effects, including:

  • Serotonin syndrome: A potentially life‐threatening problem that can happen when you take TRINTELLIX with certain other medicines. Call your doctor or go to the nearest emergency room right away if you have any of the following signs and symptoms of serotonin syndrome: agitation; seeing or hearing things that are not real; confusion; coma; fast heart beat; changes in blood pressure; dizziness; sweating; flushing; high body temperature; shaking, stiff muscles, or muscle twitching; loss of coordination; seizures; nausea, vomiting, diarrhea.
  • Increased risk of bleeding: Taking TRINTELLIX with aspirin, NSAIDs, warfarin or blood thinners may add to this risk. Tell your doctor right away about any unusual bleeding or bruising.
  • Manic episodes: Manic episodes may happen in people with bipolar disorder who take TRINTELLIX. Symptoms may include: greatly increased energy; racing thoughts; unusually grand ideas; talking more or faster than usual; severe problems sleeping; reckless behavior; excessive happiness or irritability.
  • Discontinuation syndrome: Suddenly stopping TRINTELLIX may cause you to have serious side effects including: nausea; sweating; changes in your mood; irritability and agitation; dizziness; electric shock feeling; tremor; anxiety; confusion; headache; tiredness; problems sleeping; hypomania; ringing in your ears; seizures.
  • Eye problems: TRINTELLIX may cause a type of eye problem called angle-closure glaucoma in people with certain other eye conditions. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Call your doctor if you have eye pain, changes in your vision, or swelling or redness in or around the eye.
  • Low levels of salt (sodium) in your blood: Low sodium levels in your blood that may be serious and may cause death can happen during treatment with TRINTELLIX. Elderly people and people who take certain medicines may be at a greater risk for developing low sodium levels in your blood. Signs and symptoms may include headache; difficulty concentrating; memory changes; confusion; weakness and unsteadiness on your feet which can lead to falls. In more severe or more sudden cases, signs and symptoms include: seeing or hearing things that are not real; fainting; seizures; coma; stopping breathing.

The most common side effects of TRINTELLIX include:

  • nausea
  • constipation
  • vomiting

These are not all the possible side effects of TRINTELLIX. Tell your doctor if you have any side effect that bothers you or does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

What is TRINTELLIX (vortioxetine)?

TRINTELLIX is a prescription medicine used in adults to treat a certain type of depression called Major Depressive Disorder (MDD).

There is a pregnancy registry for females who are exposed to antidepressants during pregnancy. The purpose of the registry is to collect information about the health of females exposed to antidepressants and their babies. If you become pregnant during treatment with TRINTELLIX, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants at 1-844-405-6185 or visiting online at https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/antidepressants/

For additional Important Safety Information, click here for Medication Guide, and discuss with your doctor.