The actual price you would pay is based on several factors, including your insurance coverage, which pharmacy you use, and deductibles. The list price (the total cost before insurance and/or savings offers are applied) for TRINTELLIX is $540.00 for a 30-day prescription.*

Commercially insured patients may pay as little as $10.00 for either a 30-day or 90-day prescription with the TRINTELLIX savings offer.^†

You can get an idea of the average cost you might pay below. However, your actual cost is based on your personal coverage, which may differ from the average.

Commercial (private) insurance average monthly out-of-pocket costs: $58.54

Medicare Part D average monthly out-of-pocket costs: $40.19

Medicaid average monthly out-of-pocket costs: $1.05

VA/Department of Defense insurance average monthly out-of-pocket costs: $61.00

No insurance average monthly out-of-pocket costs: $540.00

Learn more about Savings & Support.

*As of 01/01/2026.

^†Only commercially insured patients ages 18 and older are eligible for the TRINTELLIX Savings Card. The TRINTELLIX Savings Card cannot be used by patients in federal-, state-, or government-funded healthcare programs, or by cash patients. Savings of up to $100 per 30-day or $300 per 90-day prescription, with maximum total savings of $1,300 over one year. Restrictions apply. The Savings Card program will end on December 31, 2026. See Savings Card for full Eligibility Requirements and Terms & Conditions.

The TRINTELLIX Savings Card offer cannot be used if you are a beneficiary of, or any part of your prescription is covered by: (1) any federal, state, or government-funded healthcare program (for example, Medicare, Medicaid, TRICARE), including a state pharmaceutical assistance program (the Federal Employees Health Benefits (FEHB) Program is not a government-funded healthcare program for purposes of this offer), (2) the Medicare Prescription Drug Program (Part D), or if you are currently in the coverage gap, or (3) insurance that is paying the entire cost of the prescription. Patient must be age 18 or older and have a valid prescription for TRINTELLIX. Cash patients are not eligible for the TRINTELLIX Savings Card. The TRINTELLIX Savings Card program will end on December 31, 2026. This will be the final day eligible patients may enroll in and redeem the Savings Card at the pharmacy.

If eligible, you can register for the TRINTELLIX Savings Card here. If you are having trouble signing up online or have questions about eligibility requirements, you can also call 1‑866‑279‑0287 to register.

If you’re an eligible patient signing up for a TRINTELLIX Savings Card online, you will receive your activated card online immediately. You can print the Savings Card and use it right away. If you’re having trouble activating your Savings Card online, please call 1‑866‑279‑0287 to activate it.

If you received a TRINTELLIX Savings Card from your healthcare professional in the brochure, you can activate it here, or call 1‑866‑279‑0287. You will be asked for the ID number on the card.

Once you’ve activated your TRINTELLIX Savings Card, take your prescription and your Savings Card to your pharmacist.*

*Only commercially insured patients ages 18 and older are eligible for the TRINTELLIX Savings Card. The TRINTELLIX Savings Card cannot be used by patients in federal-, state-, or government-funded healthcare programs, or by cash patients. Savings of up to $100 per 30-day or $300 per 90-day prescription, with maximum total savings of $1,300 over one year. Restrictions apply. The Savings Card program will end on December 31, 2026. See Savings Card for full Eligibility Requirements and Terms & Conditions.

With the TRINTELLIX Savings Card, eligible patients can save on TRINTELLIX prescriptions and refills. You also get free access to the TRINTELLIX Support Program, tAccess, which provides support for people with MDD.

See "Am I eligible for the TRINTELLIX Savings Card?" above.

The tAccess Support Program is personalized support for patients on TRINTELLIX therapy. The purpose of the program is to help patients stay on track with their treatment as directed by their healthcare professional.Patients who enroll in the tAccess Support Program can expect to receive:

• Informative emails - Receive emails with tools to help empower you to have meaningful discussions with your doctor.
• Refill reminders when needed - Helpful medication refill reminders sent to help you along the way.
• Chats with a tAccess advisor - Call to receive information about other support features (1‑844‑654‑TRIN), 8:00 am – 8:00 pm ET M-F.

*All TRINTELLIX patients can join the tAccess Support Program. Only commercially insured patients ages 18 and older are eligible for the TRINTELLIX Savings Card. The TRINTELLIX Savings Card cannot be used by patients in federal-, state-, or government-funded healthcare programs, or by cash patients. Savings of up to $100 per 30-day or $300 per 90-day prescription, with maximum total savings of $1,300 over one year. Restrictions apply. The Savings Card program will end on December 31, 2026. See Savings Card for full Eligibility Requirements and Terms & Conditions.

If the pharmacy has difficulty processing your card, have the pharmacy follow the steps on the back of your TRINTELLIX Savings Card. The pharmacy can also call 1-866-279-0287 for processing questions.

If eligible and your pharmacist cannot process your card, or doesn’t accept your card and you’ve already paid for your prescription, please visit www.patientrebateonline.com and follow the instructions for savings. If you need further information, call 1-866-279-0287.

Patient mail-in rebate forms for eligible patients and information on how to complete and submit them are available at www.patientrebateonline.com. You may also request one by calling 1-866-279-0287.

For general information about TRINTELLIX Savings Cards, including information for getting a replacement card, call 1-866-279-0287.

Help At Hand is a patient assistance program that provides access to medicine for eligible patients with financial need. Visit Help At Hand to request an application. Restrictions apply.